Abstract
Background: To derive a simple risk score based on shear wave elastography (SWE) ultrasound to predict the individual risk of post-procedural hematoma complications in patients who underwent a percutaneous renal biopsy.
Methods: A total of 221 patients who underwent ultrasound (US)-guided percutaneous renal biopsy at our institution between April 2019 and November 2023 were enrolled in our study and randomly divided into training (n=155) or validation (n=66) cohorts. After biopsy, ultrasound was employed to evaluate the hematoma, and the maximum diameter of the hematoma was recorded for analysis. A diagnostic nomogram incorporating the selected features was established using multivariable logistic regression analysis.
Results: A total of 148 (67%) patients had postprocedure hematoma (106 and 42 patients in the training and validation cohorts, respectively), and the mean hematoma diameter was 31.12±15.01 mm (10–100 mm). The mean cortical SWE value was 42.87 kPa (21.40-69.30 kPa) for patients without hematoma and 40.18 kPa (14.90-64.50 kPa) for patients with hematoma (p=0.032). The established nomogram integrated the mean cortical swe value, triglyceride level and urinary protein level. The area under the receiver operator characteristic curve (AUC) was 0.82 in the training cohort and 0.61 in the validation cohort.
Conclusions: The risk of postprocedural hematoma complication could be assessed by a simple risk score that integrated mean cortical SWE value, triglyceride and urinary protein levels.