Abstract
Psoriasis is closely associated with cardiovascular diseases (CVD). This study aimed to investigate the relationship between Life's Essential 8 (LE8), a latest measure of cardiovascular health (CVH), and psoriasis.This population-based cross-sectional study utilized data from the 2009–2014 National Health and Nutrition Examination Survey, including a total of 7,072 participants.Multivariable logistic regression models and restricted cubic spline models were used to evaluate these correlations.Out of the 7072 participants, 204 had psoriasis.Psoriasis patients exhibited lower LE8 scores compared to non-psoriasis patients.Across all models,the high-score(80–100) group was significantly associated with a lower incidence of psoriasis compared to the low-score(0–49) group, showing a notable negative correlation between the two(OR [95% CI]: 0.437[0.225,0.810]; P<0.05).The restricted cubic spline model showed a linear association, with an LE8 value inflection point at 64.786.Negative associations were found between both health behavior and health factor scores and psoriasis. Specifically, the negative correlation was most pronounced for the nicotine exposure score.Consistent results were additionally observed in both subgroup and supplementary analyses.LE8 scores and its subscale scores were inversely related to psoriasis. Our study emphasizes that promoting optimal CVH levels may be beneficial in preventing and alleviating psoriasis.