A fluorescent probe for Hg 2+ specific recognition based on xanthene and its application in food detection and cell imaging

Author:

Zhang Chenglu1,Nie Shiru1,Liu Chang1,zhang Yang1,Guo Jinghao1

Affiliation:

1. Liaoning Normal University

Abstract

Abstract The mercury-loving unit aminothiourea was introduced into the xanthene fluorophore to synthesized the probe molecule NXH. NXH has a specific response to Hg2+, and with the addition of (0 ~ 50 µM) Hg2+, the fluorescence intensity of the probe solution was quenched from 2352 a.u. to about 308 a.u.. The probe NXH exhibited excellent detection performance of high sensitivity (LOD = 96.3 nM), real-time response (105 s), wide pH range (2.1 ~ 9.3), and strong anti-interference ability for Hg2+. At the same time, the probe NXH has wide range of applications for Hg2+ detection, which can be used to create molecular logic gates, make Hg2+ detection test paper, as well as the fluorescence imaging of Hg2+ in Hela live cells and tea samples.

Publisher

Research Square Platform LLC

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