Vitamin D Levels in the Small Newborn for Gestational Age. How Much do Maternal Levels Influence?

Author:

Pierdant-Pérez Mauricio1ORCID,Ramos-Jimenez Alicia Yasmin2,Villegas-Álvarez Carolina3,Bravo-Ramirez Ana María4,Roman-Flores Adolfo San,Flores-García José Andrés1

Affiliation:

1. Universidad Autonoma de San Luis Potosi

2. Hospital Central Dr Ignacio Morones Prieto

3. Hospital Central

4. Hospital Central "Dr. Ignacio Morones Prieto"

Abstract

Abstract Introduction: Relationship between maternal vitamin D (VitD) levels and newborn (NB) small for gestational age (SGA) is uncertain, maternal deficit may imply low levels at birth and affect evolution of NB. Objective: Determine if maternal VitD levels influence its (SGA) levels, and relationship with maternal body mass index (BMI). Material and methods: Cohort study, multiple regression model, Wilcoxon SR and Spearman's rho used to compare the VitD levels. Results: 63 mothers, 25.88 (±5.1) years, BMI 31.2 (±4) Kg/m2, median VitD 14.8 [9.05] ng/ml, VitD levels: 35 (55.5%) deficient, 13 (21%) insufficient and 15 (24%) sufficient. 68 NB 35.78 (±2.58) GW, weight 1871.98 (±449) g, 7 (10.3%) percentile <5 and 61 (89.7%) percentile 5- 10, VitD 10.1 [6.72] ng/dl, VitD levels: 6 (8.8%) severely deficient, 45 (66.2%) deficient, 10 (14.7%) insufficient and 7 (10.3%) sufficient; significantly different. Conclusions: VitD levels in overweight mothers significantly influence vitamin levels in SGA NB.

Publisher

Research Square Platform LLC

Reference30 articles.

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3. The impact of vitamin D on fetal and neonatal lung maturation: a systematic review;Lykkedegn S;Am J Physiol-Lung Cell Mol Physiol,2015

4. Bone mineral metabolism in the micropremie;Rigo J;Clin Perinatol,2000

5. Association of vitamin D deficiency with acute lower respiratory tract infections in newborns;Dinlen N;J Matern Fetal Neonatal Med,2016

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