Effectiveness of Intra-coronary Injection of Sodium Nitroprusside to The Treatment of Coronary No-Reflow Through Punctured Coronary Balloon

Abstract

Abstract Background Rapid restoration of TIMI 3 on case of no-reflow during PCI is imperative. Application of punctured coronary balloon intracoronary injection of sodium nitroprusside is a prompt, safe and effective method. Objective To investigate the effectiveness of intracoronary injection of Sodium Nitroprusside via punctured coronary balloon in the treatment of no-reflow in coronary artery.Methods: We retrospectively analyzed 76 patients treated with intracoronary injection of Sodium Nitroprusside via punctured coronary balloon for coronary no-reflow. Results All 76 patients successfully completed intracoronary injection of Sodium Nitroprusside, with the improvement of no-reflow in coronary artery to TIMI grade III in 74 patients. There were two complications occurred in the early application of this technique: one was a punctured coronary balloon fracture left in the distal coronary artery, and the other was a difficult pullbacking of the punctured coronary balloon catheter. After improving the application method, no more complication case occurred in 67 cases afterward, and no complications such as coronary guide wire pulled out of the coronary artery, coronary artery dissection, coronary artery perforation, and coronary artery air embolism occurred. Conclusion Coronary no-reflow treatment with intracoronary injection of Sodium Nitroprusside via punctured coronary balloon is safe and effective when properly applied.