Unmeasurable C-reactive Protein as a Clue in Diagnosis of Severe Hematology Pathologies in Children in Primary Settings

Author:

Piteková Barbora1,Zieg Jakub2,Konopásek Patrik2,Turecký Ladislav3,Brenner Marcel4,Gécz Jakub4

Affiliation:

1. Comenius University and National Institute of Children’s Diseases

2. University Hospital Motol, Charles University

3. Comenius University

4. National Institute of Children’s Diseases

Abstract

Abstract Fever is among the most common symptoms which lead parents and their children to the pediatrician. The most common cause of fever in children is acute infection (bacterial or viral). However, sometimes fever can be the manifestation of much more serious diseases. C-reactive protein is a marker widely used in clinical pediatric practice which helps to decide if any antibiotic treatment is needed or not. The authors present 3 case reports of children with fever from the pediatric emergency department, when the result unmeasurable capillary C-reactive protein was one of the clues in the diagnosis of severe hematology pathologies.

Publisher

Research Square Platform LLC

Reference12 articles.

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2. Delayed diagnosis of leukemia and association with morbid-mortality in children in Pernambuco, Brazil;Lins MM;J Pediatr Hematol Oncol,2012

3. Nehring SM, Goyal A, Patel BC (2022) C-Reactive Protein. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.

4. Evaluation of a quick test for C-reactive protein in a pediatric emergency department;Papaevangelou V;Scand J Clin Lab Invest,2006

5. QuikRead go CRP instructions. Available from: https://www.aidian.eu/uploads/COM-Documents-and-materials/QuikRead-go/QuikRead-go-CRP/IFUs/136061-11_QR_go_CRP_GBDEFRIT_web.pdf

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