Events of Immune Thrombocytopenic Purpura (ITP) Among COVID-19-positive Adults in the United States; an Analysis via the National Inpatient Sample for Cases Between April to November 2020

Author:

Ramphul Kamleshun1,Jala Saisree Reddy Adla2,Chennaprag Suma Sri3ORCID,Dandwani Mehndi4,Savani Saloni5,Verma Renuka6,Ajitha Salini7,Pramudita Arcita Harjani8,Singh Vaishnavi5,Kumar NOmesh9,Goyal Shriya10,Thevuthasan Sindhu10,Dhillon Balkiranjit Kaur11,Ramphul Yogeshwaree12,Aggarwal Shruti13,Dhaliwal Jasninder Singh14,Sanikommu Sailaja15,Sakthivel Hemamalini16,Sharma Shivani10

Affiliation:

1. Independent researcher

2. Centinela Hospital Medical Center

3. Louisiana State University Health Sciences Center Shreveport: LSU Health Shreveport

4. University of Iowa Hospitals and Clinics

5. : Willis-Knighton Health System

6. Kirk Kerkorian School of Medicine at UNLV: University of Nevada Las Vegas Kirk Kerkorian School of Medicine

7. TD Medical College Hospital: Thirumala Devaswom Medical College

8. Dana-Farber/Harvard Cancer Center

9. DMC Sinai-Grace Hospital

10. LSU Health Shreveport

11. : Researchers

12. Sir Seewoosagur Ramgoolam Medical College

13. Researchers

14. UC Riverside: University of California Riverside

15. sjmedspace chennai

16. Interfaith Medical Center

Abstract

Abstract

Various cases of immune thrombocytopenic purpura (ITP) were reported among COVID-19-positive patients in the literature. We used the National Inpatient Sample (NIS) to evaluate the odds of ITP among COVID-19 patients in the United States between April and November 2020. Females (vs. Males), Whites (vs. other races), and the presence of multiple comorbidities such as chronic kidney disease, cirrhosis, prior stroke, HIV, obesity, cachexia, neoplasms, and autoimmune conditions showed higher odds of ITP. Meanwhile, those with diabetes and peripheral vascular disease and covered by private insurance (vs. Medicare) were less likely to experience ITP while being positive for the virus. Events of ITP also led to a higher mortality risk in COVID-19-positive patients.

Publisher

Research Square Platform LLC

Reference13 articles.

1. Coronavirus Disease: A Review of a New Threat to Public Health;Ramphul K;Cureus,2020

2. A comprehensive review and update on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Coronavirus disease 2019 (COVID-19): what do we know now in 2021?;Ramphul K;Archives of medical sciences Atherosclerotic diseases,2021

3. Immune Thrombocytopenia Secondary to COVID-19: a Systematic Review;Bhattacharjee S;SN Compr Clin Med,2020

4. HCUP National Inpatient Sample (NIS). Healthcare Cost and Utilization Project (HCUP). 2020. Agency for Healthcare Research and Quality, Rockville, MD. 2022 [Available from: www.hcup-us.ahrq.gov/nisoverview.jsp.

5. FDA approves second. Covid vaccine for emergency use as it clears Moderna’s for U.S. distribution 2020 [Available from: https://www.cnbc.com/2020/12/18/moderna-covid-vaccine-approved-fda-for-emergency-use.html.

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