Synthesis and characterization of poly(β-alanine-b-vinyl benzyl-g-vinyl chloride) block-graft copolymers by using reversible addition-fragmentation chain transfer polymerization and 'click' chemistry

Abstract

Abstract Synthesis and characterization of poly(β-alanine-b-vinyl benzyl-g-vinyl chloride) [poly(BA-b-VB-g-VC)] block-graft copolymer was done by reversible addition-fragmentation chain transfer polymerization and 'click' chemistry. For this, poly-β-alanine with a vinyl end group was synthesized by hydrogen transfer polymerization of acrylamide. Bromine-terminated poly-β-alanine (PBA-Br) was obtained by treating the synthesized poly-β-alanine with hydrogen bromide. Poly-β-alanine ethyl xanthate (macro-RAFT agent) was synthesized using PBA-Br and potassium ethyl xanthate. Poly(β-alanine-b-vinyl benzyl chloride) [poly(BA-b-VBC)] block copolymer was obtained by reversible addition-fragmentation chain transfer polymerization of macro-RAFT agent with vinyl benzyl chloride. Azido-terminated poly(β-alanine-b-vinyl benzyl chloride) [poly(BA-b-VBC)-N3] was synthesized by the reaction of poly(BA-b-VBC) with sodium azide. Alkyne-terminated polyvinyl chloride (PVC-propargyl) was obtained by treating polyvinyl chloride with propargyl alcohol. Finally, the synthesis of poly(BA-b-VB-g-VC) block-graft copolymer was carried out by the 'click' chemistry method of poly(BA-b-VBC)-N3 and PVC-propargyl. The products were characterized by various spectroscopic and thermal methods.