Affiliation:
1. Antai Medical Care Cooperation Antai Tian-Sheng Memorial Hospital, Donggang Township, Pingtung County
2. Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine
3. Chiayi Chang Gung Memorial Hospital
Abstract
Abstract
Background:
A variety of eye drops are available for treating dry eye disease (DED). The aim of this study was to evaluate the short-term result of preservative-free potassium salt solution (PSS) as an add-on treatment for patients with DED.
Method:
This retrospective study was conducted at a tertiary referral center, and the parameters of routine clinical and instrumental evaluations at baseline, 1 month, 2 months, and 3 months after DED treatment were collected.
Results:
After PSS instillation, patients with dry eye had considerable improvements in average Ocular Surface Disease Index (OSDI) and assessable time but had a worse mean score in the temporal bulbar redness and initial tear spreading velocity. Subgroup analysis showed a considerable improvement in the OSDI, initial and stable lipid layer thickness in primary patients with DED, whereas a statistically worse average improvement in the temporal bulbar and limbal redness in patients with primary open angle glaucoma concomitant with dry eye disease.
Conclusions:
Preservative-free PSS may provide a rapid assistance on relieving the subjective and objective ocular symptoms for patients with treated DED as an add-on therapy.
Trial registration:nil
Publisher
Research Square Platform LLC