Silicone oil as a corneal lubricant to reduce corneal edema and improve visualization during vitrectomy

Author:

Che Danyang1,Chan Zhulin2,Zhou Jibo1,Zhu Dongqing1

Affiliation:

1. Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine

2. The PLA Navy Anqing Hospital

Abstract

Abstract Purpose: To evaluate the efficacy and safety of silicone oil (SO) as a corneal lubricant to improve visualization during vitrectomy. Design: A retrospective, interventional, observational study. Methods: Patients who underwent vitreoretinal surgery were divided into two groups. Group 1 was operated on with initial SO as a corneal lubricant. Group 2 was operated on with initial lactated ringer’s solution(LRS) and then replaced with SO as required. Fundusclarity was scored during the surgery. Fluorescein staining was performed to determine the damage to corneal epithelium. Results: 114 eyes of 114 patients were included. Single SO use maintained a clear cornea and provided excellent visualization of surgical image. In group 1, the fundus clarity was grade 3 in 41/45 eyes and grade 2 in 4/45 eyes. In group 2, corneal edema frequently occurred after initial LRS use. The fundus clarity was grade 3 in 19/69 eyes, 2 in 37/69 eyes and 1 in 13/69 eyes. This difference between two groups was statistically significant. SO was applied in 29 eyes of initial LRS use with subsequent corneal edema, which eliminated the corneal edema in 26 eyes. Corneal fluorescein staining score in group 1 was 0 in 28 eyes, 1 in 11 eyes and 2 in 6 eyes, and 40, 20 and 9, respectively, in group 2. This difference between two groups was not statistically significant. Conclusion: The use of SO as a corneal lubricant is effective and safe for preserving and improving corneal clarity and providing clear surgical field during vitrectomy.

Publisher

Research Square Platform LLC

Reference8 articles.

1. Frequency of epithelial debridement during diabetic vitrectomy;Friberg TR;Am J Ophthalmol,2003

2. Reduced need for corneal epithelial debridement during vitreo-retinal surgery using two different viscous surface lubricants;Garcia-Valenzuela E;Am J Ophthalmol,2003

3. Effect of lubricants on corneal thickness after vitrectomy;Siegel DT;Retina,2020

4. An antidrying corneal contact lens for a noncontact wide-angle viewing system;Ohno H;Retina,2011

5. New type of antidrying lens for vitreous surgery with a noncontact wide-angle viewing system;Chihara T;Clin Ophthalmol,2013

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3