Abstract
Objective: The effectiveness of clinical pharmacists was explored in regulating the application of antibiotics, promoting rational drug use and reducing antibiotics use density (AUD) by the refined management strategy of antibiotics.
Methods: We compared and analyzed the improvement of related indexes of antibiotics and the unreasonable application of antibiotics before and after the implementation of the program,with the help of the refined management mode
Results: From 2018 to 2021, the clinical indicators of antibiotics use at our hospital showed an overall downward trend. The utilization rate of antibiotics and the AUD in inpatients gradually decreased by 12.88% and 22.44% respectively, and the rate of microbial examination increased by 39.81%. Compared the changes in indicators, it was found that the cost of antibiotics decreased significantly. PDCA was used to improve rationality of antibiotics prophylactic use in orthopedic cases. In the evaluation of rational drug use, there was a decrease in the irrational application of antibiotics and in the proportion of preventive drug use in class I incision surgery.
Conclusion: The participation of clinical pharmacists in the refined management of antibiotics can reduce AUD and the drug costs of patients, and promote the rational application of antibiotics simultaneously.