The Prognosis of Fetal Intracardiac Rhabdomyomas

Abstract

Abstract Objective To evaluate the prenatal diagnosis, clinical presentation, and outcome of cardiac rhabdomyoma and its association with tuberous sclerosis. Methods Patients diagnosed with fetal cardiac rhabdomyoma between 2016–2022 in the perinatology department of İzmir Tepecik Training and Research Hospital were evaluated retrospectively. Data were collected from the hospital database. Results As a result of a 6-year retrospective analysis, 10 cases of fetal cardiac rhabdomyoma were identified. Two of the cases had a family history of tuberous sclerosis. Neonatal or intrauterine death occurred in 4 cases who had concomitant fetal cardiac disease and tumor size of 33 mm. Tuberous sclerosis was diagnosed in fetuses with multiple rhabdomyomas and a family history of tuberous sclerosis. In 5 patients who accepted intrauterine fetal magnetic resonance imaging, no additional finding other than rhabdomyoma was detected. It was stated that there was a trend to regression of intracardiac tumors in live-born cases. Conclusion It is thought that patients with cardiac rhabdomyoma who do not have concomitant cardiac diseases and with tumor of a small size (< 20 mm) in the intrauterine period are associated with good prognosis.