The Effect of Intravesical Stent Length and Propiverine on Ureteral Stent Related Symptoms – Prospective Randomized Controlled Trial

Author:

Can Osman1,Erkoç Mustafa2,Danış Eyyüp2,Bozkurt Muammer1,Otunctemur Alper2,Canat Lutfi1

Affiliation:

1. Basaksehir Cam and Sakura City Hospital

2. Prof Dr Cemil Tascioglu City Hospital, Turkey

Abstract

Abstract Background Ureteral double J stents are widely utilized in urolithiasis. Disturbing stent-related symptoms may occur while the stent is in location. Various medical agents and stent related solutions were examined for this problem. However, the definite drug has still not been found. We aimed to research the effect of propiverine on stent-related symptoms. Method Patients who underwent ureteroscopic stone surgery between June 2020 and May 2022 were included in the study. While the control group was untreated, the treatment group received 45 mg of propiverine daily after 1 week of the operation. Stent-related symptoms were assessed by USSQ at the end of 1st week and 3rd week of surgery. In addition, the intravesical stent parts of all patients were quantitatively measured with a ruler during stent removal at the end of 3 weeks. Results A total of 177 patients were assessed in the study. Eighty-seven of patient were control and 90 patients of them were treatment group. According to USSQ, urinary symptoms scores, body pain scores, general health scores, work performance scores, sexual health scores, additional problem scores, global QoL scores were found decreased in the treatment group (p<0.001 All domains). Intravesical stent length was found positive correlation with urinary symptom score (1st week) of all patients. Conclusion Stent-related symptoms are more likely in patients with longer intravesical stent length. Propiverine successfully relieve stent-related symptoms.

Publisher

Research Square Platform LLC

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