Risk factors for perioperative intra-aortic balloon pumping application in patients undergoing coronary artery bypass grafting：a single-center experience

Abstract

Abstract Background: There were few studies on risk factors predicting perioperative application of intra-aortic balloon pumping (IABP) in coronary artery bypass grafting (CABG) patients. The aim of the study is to explore risk factors for perioperative application of IABP in CABG patients. Methods: Patients with preoperative IABP implantation were excluded. 1337 patients undergoing CABG were finally included. Patients were divided into two groups: IABP group and non-IABP group. Medical history, biochemical and ultrasonagraphic parameters were compared between the groups. Multivariate logistic analyse was used to explore possible risk factors. Combined ROC analysis was performed and area under ROC (AUC) was used to decide diagnostic capability of the risk factors. Results: Patients in IABP group had a higher proportion of myocardial infarction (MI) history and atrial fibrillation(AF) history. IABP group also had a larger amount of blood loss and a higher serum level of small, dense low-density lipoprotein (sd-LDL). As for imaging results, IABP group had a lower Left ventricular ejection fraction (LVEF). Multivariate logistic analyse showed that LVEF< 50% (OR, 3.120) , history of MI (OR, 2.006), sd-LDL serum level (OR, 2.201) and blood loss during surgery>1000ml (OR, 2.545) were independent risk factors. Combined ROC analysis showed an AUC of 0.707. Conclusion: For CABG patients, LVEF<50%, history of MI, blood loss during surgery>1000ml and sd-LDL serum level were risk factors for perioperative application of IABP. Combined ROC analysis showed an AUC of 0.707.