A single NLR gene confers resistance to leaf and stripe rust in wheat-Reference-Cited by-同舟云学术

A single NLR gene confers resistance to leaf and stripe rust in wheat

Published:2023-07-28 Issue: Volume: Page:
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Author:

Sharon Amir¹^ORCID,Sharma Davinder¹,Avni Raz²,Gutierrez-Gonzalez Juan³^ORCID,Kumar Rakesh²^ORCID,Sela Hanan⁴^ORCID,Prusty Manas²,Cohen Arava²,Molnar Istvan⁵^ORCID,Holušová Kateřina⁵,Said Mahmoud⁶^ORCID,Doležel Jaroslav⁵^ORCID,Millet Eitan²,Khazan Sofia²,Landau Udi²,Bethke Gerit⁷,Ezrati Smadar²,Ronen Moshe²,Maatuk Oxana²,Eilam Tamar²,Manisterski Jacob²,Ben-Yehuda Pnina²,Anikster Yehoshua²,Matny Oadi⁸^ORCID,Steffenson Brian⁸^ORCID,Mascher Martin⁹^ORCID,Brabham Helen¹⁰,Moscou Matthew¹¹^ORCID,Liang Yong¹²,Yu Guotai¹³,Wulff Brande¹³^ORCID,Muehlbauer Gary⁸^ORCID,Minz-Dub Anna²

Affiliation:

1. Institute for Cereal Crops Improvement

2. Institute for Cereal Crops Research, School of Plant Sciences and Food Security, Tel Aviv University, Tel Aviv, Israel 6997801

3. University of Leon

4. University of Haifa

5. Institute of Experimental botany of the Czech Academy of Sciences

6. Institute of Experimental Botany of the Czech Academy of Sciences, Centre of the Region Haná for Biotechnological and Agricultural Research, Olomouc, Czechia

7. Department of Plant Biology, University of Minnesota, St. Paul, Minnesota 55108

8. University of Minnesota

9. Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben

10. The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK

11. USDA-ARS

12. School of Plant Sciences and Food Security, Tel Aviv University, Tel Aviv, Israel, 69978

13. King Abdullah University of Science and Technology

Abstract

Abstract Nucleotide-binding site leucine-rich repeat (NLR) disease-resistance genes typically confer resistance against races of a single pathogen. We report that Lr/Yr548, an NLR gene from Aegilops sharonensis and Aegilops longissima, confers specific resistance against Puccinia triticina (Pt) and P. striiformis tritici (Pst) that cause leaf and stripe rust, respectively. Lr/Yr548 prevented disease development in wheat introgression as well as transgenic wheat lines. Comparative analysis of Lr/Yr548 and all cloned Triticeae NLR disease-resistance genes showed that Lr/Yr548 contains a distinctive coiled-coil domain and that it is unique to Ae. sharonensis and Ae. longissima. A phylogenetic analysis indicated multiple events of gene flow of Lr/Yr548 between the two species, and suggested loss of resistance in susceptible isolates. The confinement of Lr/Yr548 to Ae. longissima and Ae. sharonensis and the cross resistance that it confers against Pt and Pst in wheat highlight the potential of these species as sources of novel disease-resistance genes for wheat improvement.

Publisher

Research Square Platform LLC

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