Study on the Osteogenesis Effect of Bio-Oss Bone Powder Combined with Medical Collagen Sponge Following Jaw Cyst Surgery

Author:

WEN Hailong1,ZHANG Tonghan2

Affiliation:

1. Jinan University

2. Hospital of stomatology,zhongshan city

Abstract

Abstract

Objective The aim of this study is to evaluate the osteogenesis effect following jaw cyst surgery by comparing three scenarios: no use of filling materials, the use of a medical collagen sponge alone, and the combined application of Bio-Oss bone powder with a medical collagen sponge. This comparison aims to provide evidence for selecting appropriate filling materials for post-surgical treatment of jaw cysts. Methods This research involved 52 patients with jaw cysts at the Zhongshan City Stomatological Hospital from October 2022 to September 2023. Patients were randomly assigned to three groups: Group A (control group with no filling material), Group B (medical collagen sponge), and Group C (Bio-Oss bone powder combined with a medical collagen sponge). CBCT scans were taken before surgery and at 3 and 6 months post-operation. The Mimics 21.0 software was utilized to analyze changes in the volume of the cyst cavity and the bone density values. Results Significant statistical differences in changes to the volume of the cyst cavity and bone density were observed among the three groups (P < 0.01). Group C demonstrated the most effective osteogenesis, with a reduction in cyst cavity volume by 51.74% and an increase in bone density by 321.24% at 3 months post-operation. By 6 months, the cyst cavity volume had decreased by 80.54%, and the bone density had increased by 422.72%. Group B had the second-best outcomes, while Group A had the least effective bone regeneration. Conclusion The study concluded that the combination of Bio-Oss bone powder and medical collagen sponge leads to the most effective osteogenesis in patients undergoing surgery for jaw cysts. The use of a medical collagen sponge alone was the second most effective, while no filling material resulted in the least effective postoperative bone regeneration.

Publisher

Research Square Platform LLC

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