Abstract
Background
Outlet obstruction constipation is the main type of chronic constipation, and has a serious impact on people's lives. However, the factors affecting symptom severity and quality of life are still unclear. This study aimed to analyze factors affecting symptom severity and quality of life in patients with outlet obstructive constipation.
Methods
General clinical information of patients with outlet obstructive constipation from July 2021 to January 2023 were collected continuously by means of a cross-sectional survey. Symptom severity was assessed by the Obstructive Defecation Syndrome scale, and quality of life was assessed by the Patient Assessment of Constipation -Quality of Life scale.
Results
The multiple linear regression analysis showed that: Delivery times (β = 0.114, p = 0.011), drinking less than 1000 ml of water per day (β = 0.106, p = 0.007), lower intake of vegetables and fruits (β = 0.118, p = 0.004), higher SAS score (β = 0.230, p < 0.001), lean (β = 0.088, p = 0.009), smoking history (β = 0.129, p = 0.002), laxative use (β = 0.273, p < 0.001), disease duration > 10 years (β = 0.237, p < 0.001), and perianal disease (β = 0.072, p = 0.042) were independent risk factors for ODS scores; Delivery times (β = 0.114, p = 0.011), drinking less than 1000 ml of water per day (β = 0.113, p = 0.007), intake of fewer vegetables and fruits (β = 0.123, p = 0.004), higher SAS score (β = 0.389, p < 0.001), lean (β = 0.099, p = 0.006), laxative use (β = 0.198, p < 0.001), squatting stool (β = 0.136, p < 0.001), disease duration > 10 years (β = 0.159, p < 0.001), and perianal disease (β = 0.082, p = 0.028) were independent risk factors for PAC-QOL scores.
Conclusions
There are several independent risk factors that significantly impact symptom severity and quality of life in individuals with outlet obstructive constipation.