Health-related Quality-of-life outcomes following Roux-en-Y-Gastric-Bypass versus One-Anastomosis- Gastric-Bypass

Abstract

Abstract Purpose Roux-en-Y-Gastric-Bypass (RYGB) and One-Anastomosis-Gastric-Bypass (OAGB) are effective standard bariatric surgeries with comparable weight loss and remission of obesity-related comorbidities. As procedure-specific health-related quality-of-life (HrQoL) outcomes have not been directly compared thus far, we conducted this questionnaire-based study. Methods 240 patients after undergoing either RYGB or OAGB between 2011 and 2016 were contacted and asked to fill out SF36 and BAROS questionnaires. All statistical analysis was performed with Microsoft Excel and GraphPad Prism. Primary objectives were procedure-dependent differences in HrQoL. Secondary objectives were weight loss and remission of comorbidities. Results 119 of 240 contacted patients (49.6%) replied, 58 after RYGB (48.7%) and 61 after OAGB (51,3 %). Follow-up period was <24 months in 52 and >24 months in 64 evaluable patients. Mean age was 46 years (range 23 to 71). Regarding the <24 months groups, both physical and psychological SF36 sum scales were comparably high. Only the subcategory “general health perception“ was significantly better after RYGB. Significantly higher excess weight loss (EWL) after RYGB (88.81%) compared to OAGB (66.25%) caused significantly better global <24 months BAROS outcomes, whereas remission of comorbidities and HrQoL were similar. Both >24 months groups showed high SF36-HrQoL sum scales. Global mean BAROS results after >24 months were “very good“ in both procedures. EWL in RYGB (80.81%) and in OAGB (81.36%) were comparably excellent. Conclusion Concerning SF36 and BAROS evaluated HrQoL in early and late postoperative phases, both procedures demonstrated comparable and relevant improvements. Further (preferably randomized) studies should include evaluation of preoperative HrQoL.