Combined (resistance-endurance) home based training and red grape juice supplementation improve memory in MS patients

Abstract

Abstract Background In recent years, attention to the improvement of memory in Multiple Sclerosis (MS), patients is less investigated. Hence, for the first time, in this study deals with the relationship between combined training and red grape juice supplementation with memory improvement in MS patients. Method In this study, 48 women with MS with an age range of 20-40 years were selected and placed in 4 groups: traning (n=12), supplement (n=12), training+supplement (n=12), and control (n=12). Combined training for 8 weeks (3 sessions per week) was performed for 60 minutes with an intensity of 10-12 Rate of Perceived exertion. Supplementation for 8 weeks (3 sessions per week), 250 ccs of red grape juice with Brix 14 was consumed. Before and after the intervention, memory was evaluated by a daily memory questionnaire and retrospective and prospective memory. The obtained data were calculated using the analysis of variance test at a significant level (P ≤0.05). Results The results show a significant improvement in daily memory and retrospective and prospective memory in the traning, supplement, and trianing + supplement groups, respectively (P=0.000), (P=0.000), (P=0.000) compared to the group it was controling. The results of the post hoc test also show the difference between the groups with each other (P ≤0.05). Conclusions Red grape juice supplementation with 8 weeks of combined training improves cognitive disorders (memory) in MS patients.