The impact of fetal gender on pregnancy and neonatal outcomes in twin gestation

Abstract

Abstract Objective: This study aimed to examine the influence of fetal gender on obstetric outcomes in twins based on their location in the uterus. Study design: Retrospective study. Maternal and obstetrics outcomes were compared among three groups: male-male, female-female, and male-female groups. Comparison of neonatal outcomes was performed between four groups: male A-male B, male A-female B, and female A-male B, female A-female B groups. Results: A total of 1073 twin gestations were included, comprising 288 male-male, 288 female-female, and 497 male-female groups. Higher rates for NICU admission were observed when fetus A was male compared to female. Adverse composite neonatal outcome was more common in the male-male group, compared to female-male group, and compared to female-female group. Conclusion: Twin gestation with first twin male tends to have worse neonatal outcome compared to those with a first twin female. The presence of a male co-twin increases the risk of adverse outcome.