Green synthesis of copper oxide nanoparticles using Spinacia oleracea leaf extract and evaluation of biological applications: antioxidant, antibacterial, larvicidal and biosafety assay

Abstract

Abstract Copper nanoparticles (Cu-NPs) recently engrossed the attention of investigators due to their incredible features and numerous applications in the pharmacological industry. This research work focuses on the manufacture of copper oxide nanoparticles in an aqueous media utilizing Spinacia oleracea leaf extract. Various analytical methods like UV/Vis Spectroscopy, FT-IR spectroscopy, X-Ray diffraction studies, SEM analysis were utilized to identify structure of the CuO nanoparticles produced. The CuO nanoparticles exhibited significant bactericidal action towards Staphylococcus aureus, Escherichia Coli, proteus, klebsiella & potential antifungal activity towards A.flavus, Rhizopus & A.fumigant. Furthermore,the synthesized CuO nanoparticles have significant larvicidal activity towards Culex. Quinquefasciatus. This research shows that CuO can be synthesized in a simple, environmentally friendly way and has a wide range of uses.