Analysis of the diagnostic flow of cutaneous leishmaniasis in the state of Minas Gerais-Brazil-Reference-Cited by-同舟云学术

Analysis of the diagnostic flow of cutaneous leishmaniasis in the state of Minas Gerais-Brazil

Published:2023-12-21 Issue: Volume: Page:
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Author:

Medeiros Fernanda Alvarenga Cardoso¹,Filho Job Alves Souza²,Reis Ilka Afonso³,Menezes-Souza Daniel⁴,Silva Aline Fagundes da⁵,Marcelino Andreza Pain⁵

Affiliation:

1. Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade Federal de Minas Gerais

2. Serviço de Doenças Parasitárias da Divisão de Epidemiologia e Controle de Doenças da Diretoria do Instituto Octávio Magalhães da Fundação Ezequiel Dias, Belo Horizonte-MG, Brasil;

3. Instituto de Ciências Exatas da Universidade Federal de Minas Gerais, Belo Horizonte-MG

4. Departamento de Patologia Clínica do Colégio Técnico da Universidade Federal de Minas Gerais, Belo Horizonte-MG

5. LaPClinVigiLeish-Instituto Nacional de Infectologia Evandro Chagas da Fundação Oswaldo Cruz, Rio de Janeir-RJ

Abstract

Abstract Objective To assess the performance of the proposed new diagnostic pathway in patients with suggestive clinical symptoms of CL within MG's public laboratory network. Methods This is a descriptive study where the results of CL tests were analyzed in patients with clinical suspicion of the disease who had their tests conducted within MG's public laboratory network and the results were registered in the Laboratory Management System of the Ezequiel Dias Foundation, during the period from 2017 to 2020. Results Out of a total of 1,369 individuals analyzed, the diagnosis of CL was confirmed in 704 (51.4%), with 610 (86.7%) through DPE and 94 (13.4%) through PCR. Additionally, 53 (25.3%) patients with negative DPE results showed positive PCR results. Conclusion The proposed CL diagnostic pathway in MG proved to be effective as it ensures that the initial test is conducted on-site, allowing for greater access and efficiency in the treatment of confirmed cases. PCR demonstrated to be an effective confirmatory test.

Publisher

Research Square Platform LLC

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