Affiliation:
1. Inje University Busan Paik Hospital
Abstract
Abstract
Purpose
The purpose of this study was to analyze the changes before and after 25-gauge pars plana vitrectomy (PPV) using an ocular surface analyzer.
Methods
The medical records of 82 patients and 163 eyes who underwent PPV were reviewed retrospectively. Non-invasive tear film break-up time (NITBUT), lipid layer thickness, meibomian gland loss, and tear meniscus height were measured at before surgery, one month, and three months after surgery. The changes in each index were statistically analyzed. In addition, risk factors that could reduce NITBUT at one month after surgery were analyzed.
Results
One month after surgery, the NITBUT was significantly decreased in the operative eyes compared to before surgery (p = 0.006, paired t-test). Compared with non-operative eyes, NITBUT in operative eyes decreased significantly at one month after surgery (p = 0.006, student t-test). Age (β=-0.248, p = 0.029, multiple linear regression) and preoperative NITBUT (β = 0.357, P = 0.002, multiple linear regression) were identified as significant risk factors associated with the decrease in NITBUT at one month after surgery.
Conclusion
25-gauge PPV can significantly reduce NITBUT at one month after surgery, and the risk factors are age and preoperative NITBUT. This may contribute to the development of dry eye disease after surgery.
Publisher
Research Square Platform LLC