Effects of Dietary Selenized Bacillus subtilis Peptidoglycan on Growth Performance Immunity and Antioxidant Function of Carp (Cyprinus carpio haematopterus)

Abstract

Abstract The purpose of this experiment was to study the effect of adding selenized Bacillus subtilis peptidoglycan (Se-PG) in feed on the growth performance, immunity, and antioxidant function of carp (Cyprinus carpio haematopterus). Healthy carp were fed with five experimental diets supplemented with 0 (control group), 50, 100, 200, and 400 mg/kg Se-PG for 56 days. Each group had three replicates with 30 fish per replicate. The results were as follows. The weight gain rate and specific growth rate of the experimental group were significantly higher than those of the control group (P < 0.05). Compared with the control group, the IgE, IgG, IgM, complement 3, and interleukin 10 (IL-10) contents of the experimental group significantly increased (P < 0.05), whereas the interleukin 1β (IL-1β), interleukin 2 (IL-2), and tumor necrosis factor α (TNF-α) in the serum of the experimental group significantly decreased (P < 0.05). Compared with the control group, the total antioxidant capacity (T-AOC) and catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase activities (GPx) in the hepatopancreas of the experimental group significantly increased (P < 0.05). The results indicated that adding Se-PG in feed can remarkably promote immunity and antioxidant function to increase the growth of carp, and 400 mg/kg Se-PG is the optimum dose.