Abstract
Objective
The aim of this study was to investigate the current status and correlation between psychological distress and sleep quality in hematopoietic stem cell transplantation, and to identify risk factors affecting psychological distress and sleep quality in patients.
Methods
This study investigated 275 patients who underwent hematopoietic stem cell transplantation in the laminar flow research unit of West China Hospital of Sichuan University. Surveys were conducted after they underwent transplantation, including demographic characteristics, the West China Heart Clearance Index score, and the Pittsburgh Sleep Quality Index.
Results
Anxiety and depression were present in 106 of the 275 patients. 198 patients had sleep disturbances. Sleep quality was significantly associated with anxiety and depression. Length of hospitalization, transplant complications and sleep disorders were risk factors for anxiety and depression. Transplant complications and anxiety and depression were risk factors for sleep disorders.
Conclusion
Hematopoietic stem cell transplant patients commonly experience anxiety, depression, and sleep disturbances during hospitalization. Early assessment and intervention can improve patient prognosis and quality of life in the mid- and long-term.