Biventricular hypertrophy unveiling acromegalic cardiomyopathy: A rare case report shedding light on cardiac manifestations

Abstract

Abstract Background: Acromegalic cardiomyopathy is a significant cardiovascular complication associated with acromegaly, a rare condition caused by excessive growth hormone production from a pituitary adenoma. While acromegaly often presents with distinct physical changes, early diagnosis can be challenging due to its insidious nature, leading to delayed recognition and the presence of multiple comorbidities at the time of diagnosis. Cardiovascular disease is the most common comorbidity in acromegaly, contributing to significant morbidity and mortality. Case presentation: This case report describes a non-hypertensive patient who presented with biventricular hypertrophy, revealing the presence of acromegalic cardiomyopathy at the age of 54. The diagnosis relied on information from clinical examination, imaging tests, and biological data. The patient successfully underwent transsphenoidal surgery to remove the pituitary adenoma, resulting in a positive outcome. Conclusions: Acromegaly patients have higher mortality rates compared to healthy individuals due to the wide array of associated comorbidities, consequently leading to a reduced life expectancy. Hence, early diagnosis and management, particularly before the age of 40, play a crucial role in mitigating the cardiovascular risks associated with acromegaly.