The burden of acute hepatitis C from 1990 to 2019 at the global, regional, and national level

Author:

Ouyang Guoqing1,Wang Kunpeng2,Liu Zhipeng1,Yuan Guandou1,Wang Weixing2,Mo Jinggang3,Jin Chong3,Yang Xin4,he songqing1

Affiliation:

1. The First Affiliated Hospital of Guangxi Medical University

2. Renmin Hospital of Wuhan University: Wuhan University Renmin Hospital

3. Taizhou Central Hospital

4. The Second Xiangya Hospital of Central South University

Abstract

Abstract Aims Global healthcare costs are significantly increased by acute hepatitis C. In this study, our goal was to assess the prevalence, incidence, and years lived with disability (YLDs) of acute hepatitis C globally in terms of numbers, age-standardized rates (ASRs), and percent changes. Methods Data on acute hepatitis C were acquired from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Numbers, ASRs, and percent changes of prevalence, incidence, and YLDs’ rates per 100,000 population were systematically analysed using the GBD 2019 modelled data. Results In 2019, acute hepatitis C numbers were 636,315.62 (95% uncertainty interval (UI): 560,704.41–736,991.98), 5,514,735.38 (95% UI: 4,859,438.18–6,387,263.87) and 8914.5 (95% UI: 4256.87–17539.11) for the point prevalence, incidence, and YLDs, respectively. The ASRs were 8.53 (95% UI: 7.54–9.88), 73.93 (95% UI: 65.33–85.60), and 0.12 (95% UI: 0.06–0.24) per 100,000 population for the point prevalence, incidence, and YLDs, respectively. From 1990 to 2019, the percent changes in the age-standardized prevalence, incidence, and YLDs rates decreased. Moreover, Central Sub-Saharan Africa, Central Asia, and Western Sub-Saharan Africa had the highest age-standardized prevalence, incidence, and YLDs rates in 2019. Notably, China exhibited the largest decrease in percentage change in the ASR prevalence, incidence, and YLDs from 1990 to 2019. Additionally, Egypt, Mongolia, and Angola had the highest burden of acute hepatitis C from 1990 to 2019. Conclusions Globally, the burden of acute hepatitis C has decreased significantly in many countries over the last 30 years. However, it continues to increase in low-income countries. Therefore, more international cooperation and multifaceted and multisectoral actions are required for the better monitoring of acute hepatitis C.

Publisher

Research Square Platform LLC

Reference26 articles.

1. Global trends and the impact of chronic hepatitis B and C on disability-adjusted life years[J];Nicolette Veracruz RG;Liver Int,2022

2. of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019[J];Global burden;Lancet,2020

3. Global epidemiology and burden of HCV infection and HCV-related disease[J];Thrift AP;Nat Rev Gastroenterol Hepatol,2017

4. Zeng D-Y, Li J-M, Lin Su, Dong X, You J, Qing-Qing Xing ,et al. Global burden of acute viral hepatitis and its association with socioeconomic development status, 1990–2019[J]. J Hepatol, 2021,75(3):547–556.

5. Global, regional, and national burden of neck pain in the general population, 1990–2017: systematic analysis of the Global Burden of Disease Study 2017[J];Saeid Safiri A-A;BMJ,2020

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3