Outcomes Up to Age 36 Months after Congenital Zika Virus Infection – U.S. States-Reference-Cited by-同舟云学术

Outcomes Up to Age 36 Months after Congenital Zika Virus Infection – U.S. States

Published:2023-01-16 Issue: Volume: Page:
ISSN:
Container-title:
language:
Short-container-title:

Author:

Neelam Varsha¹,Woodworth Kate R.¹,Chang Daniel J.²,Roth Nicole M.¹,Reynolds Megan R.¹,Akosa Amanda¹,Carr Christopher P.²,Anderson Kayla N.¹,Mulkey Sarah B.³,DeBiasi Roberta L.³,Biddle Cara³,Lee Ellen H.⁴,Elmore Amanda L.⁵,Scotland Sarah J.⁶,Sowunmi Similoluwa⁷,Longcore Nicole D.⁸,Ahmed Muhammad⁹,Langlois Peter H.¹⁰,Khuwaja Salma¹¹,Browne Shea Elizabeth¹²,Lind Leah¹³,Shim Kyoo¹⁴,Gosciminski Michael¹⁵,Blumenfeld Rachel¹⁶,Khuntia Shreya¹⁷,Halai Umme-Aiman¹⁸,Locklear Autumn¹⁹,Chan Mary²⁰,Willabus Teri'²¹,Tonzel Julius²²,Marzec Natalie S.²³,Barreto Nianest Alers²⁴,Sanchez Connie²⁵,Fornoff Jane²⁶,Hale Shelby²⁷,Nance Amy²⁸,Adibhatla Sowmya N.²⁹,Potts Emily³⁰,Schiffman Elizabeth³¹,Raman Devin³²,McDonald Morgan F.³³,Stricklin Brandi³⁴,Ludwig Elizabeth³⁵,Denson Lindsay³⁶,Contreras Dianna³⁷,Romitti Paul A.³⁸,Ferrell Emily³⁹,Marx Meghan⁴⁰,Signs Kimberly⁴¹,Cook Amie⁴²,Beauregard Suzann⁴³,Orantes Lucia C.⁴⁴,Cronquist Laura⁴⁵,Roush Lesley⁴⁶,Godfred-Cato Shana¹,Gilboa Suzanne M.¹,Meaney-Delman Dana¹,Honein Margaret A.¹,Moore Cynthia A.¹,Tong Van T.¹

Affiliation:

1. Centers for Disease Control and Prevention

2. Oak Ridge Institute for Science and Education

3. Children’s National Hospital, D. C.

4. New York City Department of Health & Mental Hygiene

5. Florida Department of Health

6. Massachusetts Department of Public Health

7. California Department of Public Health

8. New York State Department of Health

9. New Jersey Department of Health

10. Texas Department of State Health Services

11. Houston Health Department

12. Virginia Department of Health

13. Pennsylvania Department of Health

14. Dallas County Health and Human Services

15. Rhode Island Department of Health

16. Philadelphia Department of Public Health

17. District of Columbia Department of Health

18. Los Angeles County Department of Public Health

19. North Carolina Department of Health and Human Services

20. Washington State Department of Health

21. Georgia Department of Public Health

22. Louisiana Department of Health

23. Colorado Department of Public Health and Environment

24. Hawaii Department of Health

25. Hidalgo County Health & Human Services Dept.

26. Illinois Department of Public Health

27. Ohio Department of Health

28. Utah Department of Health

29. Wisconsin Department of Health Services

30. Indiana Department of Health

31. Minnesota Department of Health

32. Southern Nevada Health District

33. Tennessee Department of Health

34. Arkansas Department of Health

35. Nebraska Department of Health and Human Services

36. Oklahoma State Department of Health

37. Arizona Department of Health Services

38. University of Iowa School of Public Health

39. Kentucky Department for Public Health

40. South Dakota Department of Health

41. Michigan Department of Health and Human Services

42. South Carolina Department of Health and Environmental Control

43. New Hampshire Department of Health and Human Services

44. Vermont Department of Health

45. North Dakota Department of Health

46. West Virginia Bureau for Public Health

Abstract

Abstract Background: To characterize neurodevelopmental abnormalities in children up to 36 months of age with congenital Zika virus exposure. Methods: From the U.S. Zika Pregnancy and Infant Registry, a national surveillance system to monitor pregnancies with laboratory evidence of Zika virus infection, pregnancy outcomes and presence of Zika associated birth defects (ZBD) were reported among infants with available information. Neurologic sequelae and developmental delay were reported among children with ≥ 1 follow-up exam after 14 days of age or with ≥ 1 visit with development reported, respectively. Results: Among 2,248 infants, 9.9% were born preterm, and 10.0% were small-for-gestational age. Overall, 122 (5.4%) had any ZBD; 91.8% of infants had brain abnormalities or microcephaly, 23.0% had eye abnormalities, and 14.8% had both. Of 1,881 children ≥ 1 follow-up exam reported, neurologic sequelae were more common among children with ZBD (44.6%) vs. without ZBD (1.5%). Of children with ≥ 1 visit with development reported, 46.8% (51/109) of children with ZBD and 7.4% (129/1739) of children without ZBD had confirmed or possible developmental delay. Conclusion: Understanding the prevalence of developmental delays and healthcare needs these children with congenital Zika virus exposure can inform health systems and planning to ensure services are available for affected families.

Publisher

Research Square Platform LLC

Reference31 articles.

1. Development of Infants With Congenital Zika Syndrome: What Do We Know and What Can We Expect?;Wheeler AC;Pediatrics,2018

2. Vital Signs: Update on Zika Virus-Associated Birth Defects and Evaluation of All U.S. Infants with Congenital Zika Virus Exposure - U.S. Zika Pregnancy Registry, 2016;Reynolds MR;MMWR Morbidity and mortality weekly report,2017

3. Birth Defects Among Fetuses and Infants of US Women With Evidence of Possible Zika Virus Infection During Pregnancy;Honein MA;JAMA,2017

4. Rice ME, Galang RR, Roth NM, Ellington SR, Moore CA, Valencia-Prado M, et al. Vital Signs: Zika-Associated Birth Defects and Neurodevelopmental Abnormalities Possibly Associated with Congenital Zika Virus Infection - U.S. Territories and Freely Associated States, 2018. MMWR Morbidity and mortality weekly report. 2018; 67 (31): 858 – 67.

5. Neurodevelopment of 24 children born in Brazil with congenital Zika syndrome in 2015: a case series study;Alves LV;BMJ Open,2018