Affiliation:
1. Giresun Üniversitesi Tip Fakültesi: Giresun Universitesi Tip Fakultesi
2. Sakarya Training and Research Hospital: Sakarya Universitesi Egitim ve Arastirma Hastanesi
3. Giresun University Faculty of Medicine: Giresun Universitesi Tip Fakultesi
4. Sakarya University Faculty of Medicine: Sakarya Universitesi Tip Fakultesi
Abstract
Abstract
Objective: Acute mesenteric ischemia (AMI) is a vascular emergency resulting from decreased blood flow caused by the occlusion of the mesenteric vessels, hypoperfusion or vasospasm. This study aimed to investigate the prognostic value of the fibrinogen-to-albumin (FAR) ratio in patients with acute mesenteric ischemia.
Methods: A total of 91 patients were enrolled in the study. Patients' demographics such as age and gender, pre- and postoperative hemoglobin, CRP, white blood cell (WBC), neutrophils, preoperative lymphocyte, alanine transaminase (ALT), aspartate transaminase (AST), thrombocytes and postoperative D-dimer values were recorded. In addition, pre- and postoperative fibrinogen and albumin levels were recorded and FAR was calculated. Patients were divided into two groups survivors and non-survivors.
Results: The mean pre- and postoperative fibrinogen levels were statistically significantly higher in the non-survivor group than in the survivor group (p<0.001). The mean pre- and postoperative albumin levels were significantly lower in the non-survivors than in the survivors (p=0.059, p<0.001; respectively). The mean pre- and postoperative FAR ratios were considerably higher in the non-survivor than in the survivor groups (p<0.001). The change between pre- and postoperative fibrinogen, albumin and FAR values were statistically significant between the non-survivors and the survivors (for all, p<0.05).
Conclusion: The preoperative and postoperative fibrinogen levels were significantly higher, and albumin levels were significantly lower in the survivor compared to the non-survivor patients with AMI. Furthermore, the preoperative and postoperative FAR ratio was significantly higher in the non-survivors. The FAR ratio may be a valuable prognostic biomarker for patients with AMI.
Publisher
Research Square Platform LLC
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