Prevalence of Cognitive Impairment in Patients Receiving 5- Fu Containing Chemotherapy- a Systematic Review and Meta-analysis

Author:

Dsouza Anita1,Chaudhari Jyoti1,Ostwal Vikas2,Pawar Akash2,Saklani-Professor Avnish2,Rane Pallavi3,Jagdish Prathepa2

Affiliation:

1. Mahatma Gandhi Institute of Medical Sciences

2. Tata Memorial Hospital

3. Advanced Centre for Treatment, Research and Education in Cancer

Abstract

Abstract Introduction- The burden of cognitive impairment in patients who receive chemotherapy is significant. This review seeks to find out the prevalence of cognitive impairment in patients who have received 5 FU containing chemotherapy Methods- Pubmed, sciencedirect, CINAHL and Wiley were searched using the following key words in combination (cognition OR cognitive function OR cognitive impairment OR cognitive dysfunction) AND (5 FU OR 5 Fluorouracil OR chemotherapy). The reference lists of relevant studies were hand-searched to identify additional studies by two reviewers Results- The overall prevalence of cognitive in patients who received 5 FU containing chemotherapy is 29%. Discussion- Further research should study the impact of various chemotherapy protocols on cognitive functions in cancer survivors

Publisher

Research Square Platform LLC

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5. Effect of chemotherapy on Overall Survial in Contemporary metastatic prostate Cancer patients;Hoeh B;Front Oncol,2021

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