Working situation and burden of work limitations in sarcoma patients. Results from the multi-center prospective PROSa Study.

Author:

Bonilla Sergio Armando Zapata1,Fried Marius1,Singer Susanne2,Hentschel Leopold3,Richter Stephan4,Hohenberger Peter5,Kasper Bernd6,Andreou Dimosthenis7,Pink Daniel8,Arndt Karin9,Bornhäuser Martin3,Schmitt Jochen10,Schuler Marcus4,Eichler Martin3

Affiliation:

1. Clinic and Polyclinic for Internal Medicine III, haematology and medical oncology / University Centre for Tumor Diseases (UCT), University Hospital Mainz

2. Institute for Medical Biostatistics, Epidemiology and Informatics, University Hospital Mainz

3. National Center for Tumor Diseases Dresden (NCT/UCC)

4. Clinic and Polyclinic for Internal Medicine I, University Hospital Carl Gustav Carus

5. Division of Surgical Oncology and Thoracic Surgery, Mannheim University Medical Center, University of Heidelberg,

6. Interdisciplinary Tumor Center, Sarcoma Unit, Mannheim University Medical Center, University of Heidelberg, Mannheim

7. Department of Orthopedics and Trauma, Medical University of Graz

8. Sarcoma Center Berlin-Brandenburg, Helios Hospital Bad Saarow

9. German Sarcoma Foundation, Woelfersheim,

10. Center for Evidence-Based Healthcare, University Hospital Carl Gustav Carus, Technical University Dresden

Abstract

Abstract Purpose: We investigated limitations in work performance and job loss in sarcoma patients and related risk factors / predictors. Methods: We measured clinical and sociodemographic data in adult sarcoma patients from a nationwide study and recorded if the patients had dropped out of their job one year after initial assessment. Work limitations were assessed using three scales of the Work-Limitations Questionnaire (WLQ©). Analyses regarding associated factors were exploratory. Results: We included 356 patients (48.6 % female, mean age 48.3 years). After one year, 76 (21.3%) patients had dropped out of their jobs. Time since diagnosis was positively associated with staying at work (>5 years: OR 0.1; p < 0.01). Patients with liposarcoma (OR 0.1; p=0.01) were less likely to stop working. Regarding work limitations, having received sarcoma treatment in the last 6 months (Scale 1: B= 18.9; p < 0.01, Scale 2: B= 15.7; p < 0.01, Scale 3: B= 15.1; p < 0.01) was also negatively associated with limitations at the work place across all measured scales. Conclusion: Our study indicates that work limitations and job loss occur frequently in patients with sarcoma adding to the burden of this condition. The reported predictors of work limitations may help physicians to decide about the length of prescribed work inability before the start of therapy and patients in the decision about re-starting in the work life after an occurred therapy.

Publisher

Research Square Platform LLC

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