Prognostic and Therapeutic Value of LSM5 Gene in Human Brain Cancer Glioma: An Omics Database Exploration Approach

Author:

Ullah Md. Asad1,Alam Sayka1,Farzana Maisha2,Moin Abu Tayab3,Prapty Chowdhury Nusaiba Binte Sayed2,Zohora Umme Salma1,Rahman Mohammad Shahedur1

Affiliation:

1. Jahangirnagar University

2. BRAC University

3. University of Chittagong

Abstract

Abstract • This study explored the clinical relevance of LSM5 gene in glioma diagnosis and treatment for the first time • LSM5 is overexpressed in lower-grade glioma (LGG) and glioblastoma multiforme (GBM) tissues • The promoter of LSM5 gene is differentially methylated in both LGG and GBM tissues • The expression of LSM5 correlates with the survival condition and immunophenotypes of glioma patients

Publisher

Research Square Platform LLC

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