Abstract
Background
Cerebral venous sinus thrombosis (CVST) is a rare and special type of cerebrovascular disease characterized by complex etiology, diverse forms of onset, non-specific clinical manifestations, and difficult to diagnosis. Myeloproliferative neoplasm-unclassifiable (MPN-U) refers to clinical manifestations, laboratory findings, and morphological features that are consistent with the diagnosis of myeloproliferative neoplasms, but do not meet further specific classification criteria, or have overlapping features of two or more MPNs. Here, we report a case of CVST with MPN-U and a history of head trauma.
Case presentation:
A 52-year-old male was admitted the hospital due to paroxysmal visual impairment for 1 year and worsening for 2 months with a history of head trauma. His increased hemoglobin was resulted from was the MPN-U, with bilateral papilledema, impaired visual field, intracranial hypertension and elevated D-dimer, the diagnosis of superior sagittal sinus thrombosis was confirmed by brain CTV and MRI. Therefore, anticoagulant treatment with low molecular weight heparin were administered in hospital, then rivaroxaban was given after discharge. the blurred vision of this patient had significantly improved after treatment.
Conclusion
It is unique that CVST with blurred vision as the main clinical manifestation and two possible causes including head trauma and MPN-U. For patients with CVST, in addition to anticoagulant therapy, it is also necessary to identify the etiologies.