There exists a correlation between hemoglobin concentration and metabolic dysfunction

Abstract

Abstract Background The prevalence of metabolic unhealthy has emerged as a significant concern within the public health domain on a global scale. The potential correlation between hemoglobin concentration and metabolic unhealthy remains uncertain. Consequently, we endeavoured to examine this relationship both at the initial assessment and during the subsequent 3-year follow-up period. Methods A total of 4178 participants were enrolled in a 3-year follow-up study. Each participant completed a questionnaire and underwent anthropometric measurements and laboratory tests. The association between hemoglobin levels and metabolic abnormalities was evaluated using one-way ANOVA and logistic regression models. Results In comparison to the metabolically healthy group, the metabolically unhealthy group exhibited elevated baseline age, SBP, DBP, BMI, ALT, ALB, SCR, UA, FBG, TC, TG, HB, and PWV, while HDL-C was decreased. These findings were statistically significant. The prevalence of abnormal metabolism progressively increased with higher baseline hemoglobin levels. At the end of the follow-up period, hemoglobin levels were significantly higher in the metabolically abnormal group than at baseline. Furthermore, there was a positive correlation between baseline hemoglobin concentration and the incidence of metabolic abnormalities. Conclusions Monitoring the concentration of hemoglobin serves as a cost-effective and easily accessible means of detecting the onset of metabolic illness at an early stage.