Abstract
Background: Experts in hair growth (HG) from the fields of dermatology and plastic surgery routinely utilize autologous activated PRP (AA-PRP). Lyophilized growth factors (L-GFs) are a kind of PRP that has had its growth factor concentrations standardized.
Aims and objectives: To compare the effectiveness of platelet-rich plasma (PRP) injection and L-GFs injection in follicular unit extraction hair transplantation in the Crown Area of the scalp in men with androgenetic alopecia.
Subjects and methods: This research was done on forty male patients with crown area baldness with no previous treatment or hair transplant. They were divided into 2 groups: Group A: which involved 20 cases who received L-GF injections, and Group B: which included 20 cases who received PRP. Treatment was done in 3 sessions before and 3 sessions after hair transplantation using Follicular unit extraction (FUE).
Results:There was no statistically significant variance amongst the two studied groups at 1 month, 2 months, and 6 months about hair density, length, patient satisfaction, redness, surgeon satisfaction, texture, and thickness of hair. There was statistically significant variance among the studied groups (PRP and L-GF) concerning density at 3 months of the study and a highly statistically significant increased percentage of redness at 3 months.
Conclusion: PRP and L-GF therapy administered following hair transplantation are useful in that they give quicker density while simultaneously reducing the recovery period. There is not a significant distinction between the two treatments in terms of the results obtained in terms of hair density, length, patient happiness, or surgeon satisfaction. The Results of L-GF are slightly better than PRP but statistically insignificant. L-GF offers benefits over traditional autologous PRP in terms of the standardization of the preparation procedure and the great concentrations of growth factors present in L-GF.