Dexmedetomidine combined with sufentanil in intravenous controlled analgesia after hip arthrotomy in children

Abstract

Abstract Background To investigate the effect of different dose of dexmedetomidine combined with sufentanil on postoperative analgesia in children after hip arthrotomy. Methods The clinical data of 98 children who underwent hip arthrotomy in our center between January 2020 and February 2022 were selected. The children were divided into four groups according to the application of controlled analgesic drugs (sufentanil + granisetron ± dexmedetomidine). Results HR and RR in group C and D were more stable than those in group A and group B (P < 0.05). Pain scores decreased over time after treatment in all groups. When compared at the same time point, patients in Group D had the lowest pain scores, which were significantly lower than the other three groups (P < 0.05). The total consumption of sufentanil in group C and D was significantly lower than that in group A (P < 0.05). On 1st day after surgery, the children in Group D had lower levels of serum ACTH, IL-6, and COR levels than those in Group A. Conclusion Dexmedetomidine combined with sufentanil for children children with hip arthrotomy postoperative analgesia effect is exact, reduces sufentanil consumption and reduces the incidence of adverse reactions of opioids.