Cross-species single-cell annotation with orthologous marker gene groups

Author:

Li Song1,Chau Tran2,Timilsena Prakash2,Bathala Sai2,Bargmann Bastiaan2

Affiliation:

1. School of Plant and Environmental Sciences, Virginia Polytechnic Institute and State University

2. virginia tech

Abstract

Abstract The lack of known cell-type specific marker genes in most plants is a major hurdle for single-cell analysis. To address this challenge, we developed an approach to identify Orthologous Marker Gene groups (OMGs) across monocots and dicots and showed that they are capable of determining cell identities in tomato. This result indicates employing conserved OMGs from reference single-cell maps can annotate cell types in other plant species.

Publisher

Research Square Platform LLC

Reference27 articles.

1. Single-cell RNA sequencing resolves molecular relationships among individual plant cells;Ryu KH;Plant Physiol,2019

2. Single-cell transcriptome atlas and chromatin accessibility landscape reveal differentiation trajectories in the rice root;Zhang TQ;Nat Commun,2021

3. Ground tissue circuitry regulates organ complexity in maize and Setaria;Ortiz-Ramírez C;Science (1979),2021

4. A suberized exodermis is required for tomato drought tolerance;Cantó-Pastor A

5. A single-cell analysis of the Arabidopsis vegetative shoot apex;Zhang TQ;Dev Cell,2021

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3