Fabrication of dialysis membrane from cotton Giza 86 cellulose di-acetate prepared using Ac2O and NiCl2 as new catalyst

Abstract

Abstract This attempt has been made to synthesis the cellulose di-acetate in solvent-free acetylation system of cotton Giza 86 cellulose with Ac2O (200 and 300 ml) in the presence of NiCl2.6HO (1.0, 1.5 and 2.0 g) as an effectively available and new catalyst by the conventional reflux and microwave irradiation methods. This study, also illustrates the preparation of dialysis membrane which made from a cellulose di-acetate–dichloromethane- methanol-polyethylene glycol (MW: 200) casting solution. The microwave irradiation method for synthesis of cellulose di-acetate showed excellent yields and short reaction time, which is the important feature of this method. The impact of the two methods on the cellulose di-acetate formation and its used in the dialysis membrane formulations was studied. The experimental degree of substitution of the prepared cellulose di-acetate values (DS = 2.00-2.7) showed an agreement with the calculated values by FTIR and 1H-NMR analysis methods. The formation of cellulose di-acetate with percentage yields varied from 62.85 to 89.85%. The applicability of the prepared membrane in dialysis operation was evaluated in terms of urea clearance, rejection of Bovine Serum Albumin (BSA) and flux of pure water. Characterization of cellulose di-acetate was achieved through 1H-NMR, FTIR, TGA, and BET analyses. The CA-PEG blend membrane was examined by contact angle measurement, porosity, and water uptake of membrane. The cellulose acetate membrane surface morphology was determined using SEM. It is observable that, the fabricated CA-PEG blend membrane from synthesized cellulose di-acetate by using Nickel chloride as a catalyst is showing remarkably rejection of BSA and urea clearance up to 100 and 67.2%, respectively. Definitely, the present work is promising and also, applicable in dialysis membrane.