Abstract
Objective: This article plans to retrospectively analyze patients with uterine sarcoma in our hospital to determine whether expanding the surgical resection range can improve patient prognosis, increase survival rate, and prolong survival.
Methods: A retrospective analysis was conducted on 153 patients with uterine sarcoma who underwent surgical treatment in our hospital, and factors affecting their prognosis were determined through survival analysis.
Results: The Kaplan Meier survival analysis revealed that pathological grading, staging, and surgical approach were the main factors significantly affecting the 5-year survival rate of patients (p<0.05), and postoperative radiotherapy can improve the overall 5-year survival rate. Multivariate COX regression survival analysis: postoperative adjuvant radiotherapy: HR=1.277, p=0.485，95%CI= 0.643- 2.536 . Staging: HR=0.647, p=0.176，95%CI= 0.344-1.216.Surgical methods: HR=2.249, p=0.007，95%CI=1.252- 4.038.Pathological grading: HR=0.503, p=0.026 95%CI= 0.275-0.923.
Conclusion: The use of extensive hysterectomy with double adnexectomy compared to simple hysterectomy with double adnexectomy can significantly improve the overall 5-year survival rate of patients, and is an independent prognostic factor for this type of patient. Postoperative radiotherapy may prolong patient survival and improve 5-year survival rate.