Clinical study of collagen sponge combined with iRoot in apical barriers

Abstract

Abstract Background/Aim Placement of biocompatible material to obtain a good apical stop is one of the important factors that determine the success of apical barriers. The purpose of this study was to observe the clinical and radiographic outcomes of the apical plug performed using iRoot-BP, with or without collagen sponge in immature teeth with necrotic pulp, so as to provide theoretical basis for clinical application. Materials and Methods Forty-six immature teeth with necrotic pulps were included in this study. Teeth were equally divided and randomly assigned to two groups: sponge group (group KD) or control group (group NC). During apical barriers, apical plug performed with iRoot-BP or sponge + iRoot-BP followed by a permanent restoration. Blinded clinical and radiographic assessments were performed at baseline, immediate post-operative and after 3, 6 and 12 months, according to the pre-determined clinical and radiographic criteria. Results ①The evaluation results of apical lesion healing showed that 22 treated teeth in group KD (95.7%) and 21 treated teeth in group NC (91.3%) showed no clinical or radiographic signs of failure during the follow-up period (χ2 = 0.357, P = 0.55). ②The results of continuous root growth assessment showed that the root of affected teeth in group KD increased by 2 mm on average. There was statistically significant difference between group KD and group NC(P < 0.05). Conclusion Whether collagen sponge is added, iRoot-BP showed similar clinical and radiographic outcomes when used as apical barriers materials in the treatment of immature permanent teeth with necrotic pulps. However, the application of collagen sponge combined with iRoot-BP in apical barriers can promote root development of immature teeth, which is closer to the formation of normal root.