Affiliation:
1. Hospital del Mar Research Institute
2. Hospital Del Mar
3. Institut Català de la Salut
4. Universitat Politècnica de Catalunya
5. Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable
Abstract
Abstract
Background
Post-Acute COVID Syndrome (PACS) is a complex disorder that currently lacks effective evidenced-based therapies to manage it. This pilot randomized controlled trial aims to evaluate the effects of balneotherapy on PACS symptomatology.
Methods
Ninety-eight adults with PACS visited at Hospital del Mar Research Institute, Barcelona (Spain) were included to the study. Participants in the intervention group were allocated to 12 sessions of balneotherapy delivered in one month. The control group continued with their usual care. The primary outcome was to evaluate the absolute change in questionnaire scores between baseline and two follow-up points: immediately after balneotherapy (one-month post-baseline for the control group), and 2 months post-baseline. The following scales/questionnaires were employed: Post-COVID-19 functional status scale, mMRC dyspnea Scale, SF-36, Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS), Memory failures in everyday life following severe head injury, and Visual Analogic Scale (VAS).
Results
Forty-seven patients in the balneotherapy group and 43 in the control group completed the study. After balneotherapy, significant improvement was detected in the balneotherapy group vs the control group in various SF-36 domains, PSQI total score, HAD’s anxiety subscale, and VAS. Among these, SF-36’s energy/fatigue and pain subscales exhibited the most prominent changes (p-value < 0.0001). One month after balneotherapy, some of these differences were lost between groups although persisting beneficial effects were maintained particularly in SF-36’s pain and energy/fatigue scales.
Conclusion
Balneotherapy comprise a safe and tolerable rehabilitative modality that can alleviate several symptoms that characterize PACS, particularly musculoskeletal pain and fatigue.
Trial Registration:
ClinicalTrials.gov: NCT05765591 (13/03/2023)
Publisher
Research Square Platform LLC
Reference28 articles.
1. Long COVID, a comprehensive systematic scoping review;Akbarialiabad H;Infection,2021
2. Outpatient Pulmonary Rehabilitation in Patients with Long COVID Improves Exercise Capacity, Functional Status, Dyspnea, Fatigue, and Quality of Life;Nopp S;Respiration,2022
3. Effects of Multidisciplinary Rehabilitation Program in Patients with Long COVID-19: Post-COVID-19 Rehabilitation (PCR SIRIO 8) Study;Ostrowska M;J Clin Med,2023
4. Can aquatic exercises contribute to the improvement of the gait stereotype function in patients with Long COVID outcomes?;Lobanov AA;Eur J Transl Myol,2022
5. Las aguas cloruradas de los balnearios españoles;Maraver F;Aplicaciones e indicaciones MEDICINA NATURISTA,2018