Formulation & Characterization of Phytochemical Based Topical Analgesic gel in Management of Myogenous Temporomandibular Joint Pain.

Author:

Suresh Ramya1,Ramadoss Ramya1,Bargavi P1,Sundaram Meenakshi1,Krishnasamy Nitya1,G Radha1

Affiliation:

1. Saveetha Dental College and Hospitals, Saveetha University

Abstract

Abstract

Myogenous Temporomandibular joint disorder is characterised by pain & dysfunction in the masticatory muscles that are originated from pathologic and functional processes in the masticatory muscles. Most common symptoms are muscle discomfort, restricted range of motion, fatigue, stiffness, and subjective weakness. Boswellia serrata gum resin extracts have been widely employed years of years to address a wide range of chronic inflammatory conditions. These conditions include rheumatoid arthritis, osteoarthritis, asthma, inflammatory bowel disease, and other inflammatory disorders. Silver nanoparticles have a great potential for their mechanistic role. Green synthesized silver nanoparticles (AgNPs) have promising biomedical applications in healthcare. These nanoparticles are synthesized using plant-based compounds that act as moderators, resulting in AgNPs with high therapeutic potential. They offer an alternative approach to medicine utilizing the bioactive compounds of plants. The incorporation of these compounds enhances the biomedical properties of AgNPs, making them valuable for various therapeutic applications. Resinous component of Boswellia Serrata were used as a key ingredient and thymol, menthol camphor was added for topical gel formulation as it has analgesic properties which can be used for management of masticatory myalgia.

Publisher

Springer Science and Business Media LLC

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