Unexpected findings: Loss of Corneal Endothelial Cells in Uygur Patients with Exfoliation syndrome in XinJiang, China

Abstract

Abstract Purpose: This study had investigated anterior segment parameters in XFS/G patients. Methods: This was a retrospective case series. Totally 56 (112 eyes) unrelated XFS/G (XFS, 26/60 eyes; XFG, 30/44 eyes) cases and 100 (200 eyes) age-related cataract cases (control group) were assessed, who attended the ophthalmology department of the First Affiliated Hospital of Xinjiang Medical University. Clinical data, including eye axis (AL), anterior chamber depth (ACD), white to white (W-W), central corneal thickness (CCT) and corneal endothelial cell density (ECD), were collected for statistical analysis. Results: ECD significantly differed between the XFS/G and age-related cataract groups, but the remaining indexes were not statistically different. Ocular parameters in patients with XFS and XFG differed from those of age-related cataract cases, and these results were consistent. XFS and XFG patients had no statistically significant differences. Conclusions: ECD is reduced in XFS/G patients compared with age-related cataract subjects. One should still be vigilant to improve the safety of surgery in XFS/G patients and to prevent the problem before it occurs.