Ductal carcinoma in-situ arising within benign phyllodes tumours: review of the literature and case presentation

Author:

Giulia Deguidi1,Alessia Nottegar1,Marco Barillari1,Denise Fiorini1,Alessandra Invento1,Mirandola Sara1,Caldana Marina1,Tombolan Valeria1,Bertoldi Lorenzo1,Bosio Giacomo1,Pellini Francesca1

Affiliation:

1. AOUI of Verona (VR)

Abstract

Abstract

INTRODUCTION: Phyllodes tumor (PT) is a rare benign tumor of the breast with a propensity to recur and metastasize. Ductal carcinoma in situ (DCIS) within PT is an extremely rare finding and is usually diagnosed postoperatively. CASE PRESENTATION: We present a case of a 24-year-old female with bilateral multiple fibroadenomatosis and a growing lump in her right breast diagnosed as a atypical lobular hyperplasia. Preoperatively, surgical biopsy revealed DCIS within benign PT. DISCUSSION: Phyllodes tumors are rare and ones with a coexisting carcinoma are even less frequently encountered. No standard management protocol exists for such cases, but when detected by histopathology, the clinical management and prognosis have to undergo a complete change. Treatment should be guided by the type and stage of carcinoma detected and proper individualized management by a multidisciplinary team play a crucial role. CONCLUSION: Phyllodes tumors are rare and ones with a coexisting carcinoma are even less frequently encountered. No standard management protocol exists for such cases, but when detected by histopathology, the clinical management and prognosis have to undergo a complete change. Preoperative diagnosis and proper individualized management by a multidisciplinary team that ensures clear surgical margins and planned adjuvant therapy or close follow up play a crucial role in preventing the recurrence of DCIS within PT.

Publisher

Research Square Platform LLC

Reference24 articles.

1. Bernstein L, Deapen D, Ross RK. The descriptive epidemiology of malignant cystosarcoma phyllodes tumors of the breast, Cancer 71 (May (10)) (1993) 3020–3024, PMID: 8387873.

2. Primary treatment of cystosarcoma phyllodes of the breast, Cancer 89 (October (7);Chaney AW,2000

3. Orgill, the PROCESS Group, The PROCESS statement: preferred reporting of case series in surgery;Agha RA;Int J Surg,2016

4. Youngest case of ductal carcinoma in situ arising within a benign phyllodes tumour: a case report;Chopra S;Int J Surg Case Rep,2016

5. Ductal carcinoma in situ arising within a benign phyllodes tumor: a case report with a review of the literature;Nio Y;Oncol Lett,2011

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