A Modeling Investigation of the Disease Severity Driven by COVID-19-Induced Diabetic Patients

Author:

Hoque Ashabul1,Sultana Razia1,Islam Hamidul1,Malek Abdul1

Affiliation:

1. University of Rajshahi

Abstract

Abstract

In this study, we propose a new SEICHR compartmental model to investigate the transmission dynamics of COVID-19 in diabetic and non-diabetic patients. We emphasize the role of COVID-19-induced diabetic patients in disease dynamics. The well-posedness of the model and the stability of the equilibrium points are confirmed through rigorous mathematical analysis. Mathematical results are validated using numerical simulations. Sensitivity and bifurcation analyses are conducted to determine the most sensitive parameters in the proposed model. The sensitivity of the model parameters is examined using the partial rank correlation coefficients (PRCC) analysis. The results show that the disease progression rate is higher among COVID-19 infected diabetic patients than non-diabetic patients. The role of COVID-19-induced diabetic patients in driving disease severity was then analyzed through a constant and progressive delay in isolating them in hospitals. It can be observed numerically that a forward bifurcation region increases gradually with increases of the value of exposed individuals. In addition, the progressive waiting time was found to have a way greater effect on the transmission dynamics compared to the constant waiting time. Furthermore, the model outcomes could not verified in the light of real field data due to unavailability of data.

Publisher

Springer Science and Business Media LLC

Reference22 articles.

1. Optimal Control of Mathematical modeling of the spread of the COVID-19 pandemic with highlighting the negative impact of quarantine on diabetics people with Cost-effectiveness;Kouidere A;Chaos, Solitons and Fractals,2021

2. International Diabetes Federation (2021). IDF Diabetes Atlas, 10th edn. Brussels, Belgium.

3. Complexity of the Basic Reproduction Number (R0);Delamater PL;Emerging Infectious Diseases.,2019

4. Okyere S, Prah JA. (2022): A model of the transmission of SARS-Cov-2 (COVID-19) with an underlying condition of Diabetes. arXiv.

5. Anusha, S., Athithan, S. (2021). Mathematical Modelling Co-existence of Diabetes and COVID-19: Deterministic and Stochastic Approach. DOI:10.21203/rs.3.rs-862792/v1.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3