Recurrent dermatofibrosarcoma protuberans of the breast with rapid growth during pregnancy: a case report

Author:

Huang Min1,Jiang Mengyuan1,Zhang Rui1,Zhang Min2,Zhang Dengcai3

Affiliation:

1. Gansu University of Traditional Chinese Medicine

2. Gansu Provincial Hospital

3. Gansu Provincial Maternity and Child Hospital

Abstract

Abstract Background: Dermatofibrosarcoma protuberans (DFSP) is a rare soft-tissue sarcoma, with the characteristics of slow growth. Herein, we reported a unique rare case of recurrent DFSP on the breast, which rapid growth during pregnancy. Case presentation: The patient was a 35-year-old woman with recurrent tumor in left breast that as a large tumor due to rapid growth during pregnancy. Physical examination revealed the three adjacent lumps which were firm, fixed with a relatively well-defined border, and measured approximately 10×9 cm, 4×4 cm and 3×3 cm. The histopathological diagnosis was DFSP. Conclusions: We present a unique rare case of recurrent DFSP on the breast, which has rapid growing behavior during pregnancy.

Publisher

Research Square Platform LLC

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2. Dermatofibrosarcoma protuberans: update on the diagnosisand treatment;Hao X;J Clin Med,2020

3. Lim SX, Ramaiya A, Levell NJ, et al. Review of dermatofibrosarcoma protuberans. Clin Exp Dermatol.; 2022.

4. Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosomes to tyrosine kinase inhibitor treatment;Sirvent N;Genes Chromosomes Cancer,2003

5. Incidence and survival of primary dermatofibrosarcoma protuberans in the United States;Kreicher KL;Dermatol Surg,2016

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