A Biochemical Assay Provides Better Diagnosis for Active Bacterial Infections

Abstract

Abstract Bacterial infections are diseases caused by organisms of bacterial origin most of which are deadly affecting both humans and other animals. Detection of these microscopic organisms using currently available techniques in the face of reducing quality of testing reagents is increasingly becoming quite challenging especially in low prevalent settings and low density infections. The absence of a particular detection method devoid of shortcomings and pitfalls of significant order prompted the development of a simple biochemical in vitro diagnostic technique for bacteria detection known as AfiniBact Test. In this study we examined the efficacy of AfiniBact Test in detecting bacteria using culture method as the reference standard for detecting active infections on 263 patients with suspected systemic bacterial infection in Jos, Nigeria. Sensitivity/specificity of AfiniBact Test method was 97.41/70.97% respectively. The analysis showed that biochemical detection of bacterial infection using AfiniBact Test provides greater sensitivity and specificity useful for diagnostic, epidemiological and research purposes.