Are premature infants with Spontaneous Intestinal Perforation sicker than others?

Author:

Eisenstadt Michal1,Eisen Irit Schushan1,Leibovitch Leah1,Maayan-Metzger Ayala1,Gavri Ayelet1,Strauss Tzipi1

Affiliation:

1. Department of Neonatology, Edmond & Lily Safra Children Hospital, Sheba Medical Center, Tel-Hashomer, Israel, affiliated to the Sackler Facuty of Medicine, Tel Aviv University, Tel Aviv

Abstract

Abstract Spontaneous intestinal perforation (SIP) is a focal gastrointestinal complication which is diagnosed in up to 5% of the very low birth weight infants. Purpose - This retrospective case control study was designed to investigate perinatal and neonatal risk factors for SIP in premature infants who developed a SIP over a 13 years period in a single NICU. Methods - A total of 40 very low birth weight infants were include in this study. Results demonstrated that infants who developed SIP were more likely to have been born via cesarean section (80% compared to 45%, p = 0.048). They were also more likely to have been fed later (average day after delivery 3 compared to 2, p = 0.039), and were more likely to have received blood transfusions prior to SIP [OR = 7.7 (95%CI = 1.084–55.049), P = 0.041]. Infants with SIP were more likely to have received non-invasive respiratory support [OR = 0.105 (95%CI = 0.015–0.755) p = 0.025]. Conclusions - These characteristics may imply that these infants are merely sicker and hence more prone to suffer from SIP.

Publisher

Research Square Platform LLC

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