Preliminary study of fetal HQ in cardiac structure and systolic function of fetal Coarctation of the aorta

Abstract

Abstract Objective To use fetal HQ software to carry out quantitative analysis of the 4-chamber view (4-CV) and left and right ventricle of fetuses with Coarctation of aortic(CoA) and normal fetuses, and to explore the application value of this software in evaluating the cardiac structure and systolic function of fetuses with CoA. Methods fetal HQ software was used to quantitatively analyze the GSI, 24-segment SI of left and right ventricles, fractional area change (FAC) left and right ventricular area, and longitudinal contractility in 53 normal singleton fetuses and 16 fetuses with CoA, 24-segment transverse width fractional shortenin FS .p < 0.05 was considered significant. Results Compared with the two groups of fetuses, the global spherical index (GSI) was significantly different (P < 0.05), and the left ventricle 18–24 segment spherical index was significantly different (P < 0.05); the right ventricle 8-11segmental spherical index was significant differences (P < 0.05); there were significant differences in left ventricular fraction area change and longitudinal strain in the CoA group (P < 0.05); there were no significant differences in right ventricular fraction area change and longitudinal strain in the CoA group (P > 0.05); the fetal left ventricular 24-segment transverse width fractional shortening FS in the CoA group was significantly different in segments 1–12 (P＜0.05);the FS 1–4 segments were significantly different (P < 0.05). Conclusion fetal HQ technique can quickly and easily obtain the spherical index and systolic function parameters of fetal heart, and provides a new method for quantitative analysis of fetal heart structure and systolic function with CoA.