Herpes Zoster Presenting with Urinary Tract Irritation as the Initial Symptom in a COVID- 19 Patient

Author:

Cao Yuan1,Zheng Yumin2,Hu Xinhua1,Li Jun3

Affiliation:

1. Department of Neurology, People’s Hospital of Xinjin District, Chengdu

2. Department of Neurology, Shanghai Civil Aviation Hospital/Gubei Branch of Ruijin Hospital

3. Department of Urology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China

Abstract

Abstract

Background Bladder symptoms, an atypical manifestation of herpes zoster (HZ), usually occur after a vesicular eruption and can present as urinary retention or loss of sensation, especially in immunocompromised patients. Here, we report a case of a patient who presented with urinary irritation preceding the skin lesion symptoms while concurrently experiencing COVID-19. Case presentation A 67-year-old male presented with repeated episodes of frequent micturition. Initial examinations, including blood tests, urinalysis, and ultrasound of the urinary system, ruled out urinary infection or organic disorder. The patient was subsequently diagnosed with COVID-19 and received in-home treatment. Despite resolution of COVID-19 symptoms, urinary irritation persisted. Unusual skin changes in the groin area were observed, leading to a diagnosis of herpes zoster. As herpes zoster improved, urinary symptoms gradually eased, and the patient returned to his pre-illness condition by discharge. Conclusions This case highlights an atypical presentation of herpes zoster with urinary tract irritation preceding the characteristic skin rash, potentially leading to initial diagnostic misjudgment. The patient's symptoms emerged following a COVID-19 infection, suggesting a possible link between SARS-CoV-2 and the reactivation of varicella-zoster virus. Early recognition and appropriate management of such atypical presentations are crucial, especially in post-COVID-19 patients.

Publisher

Springer Science and Business Media LLC

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